The jokes can get pretty random on Family Guy, but this week there will be some high-powered star wattage powering one such gag: Johnny Depp. The film star makes his debut on the animated comedy by voicing one of his most memorable and sharpest characters from the big screen, Edward Scissorhands.

In the episode, which airs Sunday at 9 p.m. on Fox, Lois goes through a mid-life crisis and starts acting like someone half her age. As Chris, Meg, Stewie, and Brian wonder what’s wrong with her, Depp appears in a cutaway gag playing the titular character from Edward Scissorhands… as a night nurse. What will happen when Johnny reprises this iconic role for nearly 20 seconds? Press play and hold your babies tight.

Watch the video HERE!!!

Johnny Depp performs as a guest guitarist Onstage during the Petty Fest at El Rey Theatre in Los Angeles, California on Wednesday, November 14, 2012. He’s seen on many pictures ogether with bassist Michael Jared Followill of Kings of Leon rocking the stage. Check them out!

Supermodel Kate Moss opens up to Vanity Fair about her insecurities, her modeling career and her love affair with Johnny Depp. During their romance (1994-1998), Moss says she finally felt taken care of.

“There’s nobody that’s ever really been able to take care of me,” she says. “Johnny did for a bit. I believed what he said. Like if I said, ‘What do I do?,’ he’d tell me. And that’s what I missed when I left. I really lost that gauge of somebody I could trust. Nightmare. Years and years of crying. Oh, the tears!

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Depp and Moss were the It Couple and Moss was far more famous than the actor in those years. Together they attended several Cannes Film Festivals and his Donnie Brasco and Don Juan De Marco premieres. They even walked the red carpet at the 1995 Golden Globe Awards.

Depp used to go backstage when she did fashion runway shows in New York, London and Paris. Asked by this reporter why he was backstage at a Calvin Klein show in those years, Depp smiled and said, “To be with my girl.”

The couple also made tabloid headlines. Most notably when, in the wee hours of morning on Sept. 13, 1994, police were called to New York’s Mark Hotel, where they found Depp and Moss sitting in their trashed, $1,200-per-night presidential suite. Depp blamed the mess on an armadillo he said was hiding in his closet but the creature was never found. The couple was billed $9,767 for the damages, according to People.